This is an interesting thread
https://boards.4chan.org/pol/thread/321447603After going over the primary literature of COVID-19, I determined how it causes severe illness. It's a cascade that goes something like this:
>SARS-CoV-2 S binds to ACE2, its E protein acts as a calcium ion channel, and its other proteins inhibit cellular Nrf2 and suppress interferon response
>ACE2 is lost, disinhibiting Angiotensin II and des-arg9-bradykinin
>Intracellular calcium overload and prostaglandin release occurs
>Cells start producing large quantities of superoxide ROS
>Superoxide depletes endothelial nitric oxide down to nothing, forming peroxynitrite that creates a vicious cycle of NO depletion by its decoupling of nitric oxide synthase due to oxidation of tetrahydrobiopterin
>Uncontrolled replication begins with no NO left to suppress it
>Neutrophils are summoned to the inflammation site and neutrophilia/NETosis sets in
>ROS starts attacking mitochondrial aconitase and iron regulatory proteins because of their iron-sulfur groups, releasing free iron
>Hypochlorous acid from neutrophils destroys heme and releases free iron
>Free iron, hydrogen peroxide, and superoxide react through the Haber-Weiss and Fenton reactions to form hydroxyl radicals
>Hydroxyl radicals start forming oxidized lipids; oxidized phospholipids, oxidized LDL cholesterol, oxidized cardiolipin
>Oxidized fats promote autoimmunity (the body sees them as non-self and makes antibodies against them), trigger PRRs, and summon even more leukocytes
>Vicious cycle of lipid peroxidation destroys cells with ferroptosis
This is preventable with Ranitidine, Apocynin, NAC, Vitamin D, et cetera, because these things are all antioxidants. Zantac actually prevents hydroxyl radical formation. Guess which substances the FDA is trying to take off the market? The exact things that treat COVID-19. Bing Liu was killed because he was an expert in iron metabolism and he knew the truth.
